Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient.

نویسندگان

  • Kuan-Nien Chou
  • Yu-chieh Lin
  • Ming-Ying Liu
  • Ping-Ying Chang
چکیده

Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas. TMZ has been reported to cause secondary myelodysplastic syndrome and acute myeloid leukemia. However, TMZ-related acute lymphoblastic leukemia is rare. Here we describe a 54-year-old woman with glioblastoma multiforme, who developed precursor-B acute lymphoblastic leukemia with translocation (4;11)(q21;q23) after 15 months of TMZ treatment.

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عنوان ژورنال:
  • Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

دوره 21 4  شماره 

صفحات  -

تاریخ انتشار 2014